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CoQ10 is Great, but Which Kind?

 

 


CoEnzyme Q10 (CoQ10) has held its stature in the health world for years and for good reason.  CoQ10 is a naturally occurring, water soluble compound found in the mitochondria (the cell’s powerhouse) of nearly every single cell in our body.  This enzyme is most concentrated in the vital organs and is the main contributor to giving cells life.  The heart is the organ with the most concentration of CoQ10.  In fact, a study shows that there is a direct correlation between chronic heart failure have low CoQ10 counts.  The study also shows that supplementing CoQ10 and Vitamin D can considerably lower the health risk with those who have chronic heart failure.1  Another study performed in Sweden shows a significant reduction in cardiovascular mortality in elderly people when consistently supplementing with CoQ10 and Selenium.2


Ubiquinone and Ubiquinol 


Ubiquinol is the reduced form of CoQ10 which means when it is oxidized, it turns into ubiquinone.  It has been available in supplement form since 2006.  Ubiquinol is essentially an antioxidant.  It also recycles ubiquinone, vitamin C and vitamin E through it’s synthesis of energy.3


Science stuff:  Ubiquinol is involved in all body processes requiring energy: energy synthesis, active transport, membrane and nucleotide stability, synthesis of enzymes, coenzymes, hormones, neuro-transmitter synthesis and reuptake, cillary activity in the upper respiratory systems, all muscle contractile functions, sperm production and motility, deactivation of muscle contraction, pumping action of sweat and other cutaneous glands, etc.3


Ubiquinone is the oxidized form of CoQ10 and was discovered in 1957 by bio-chemist, Frederick Crane.  Ubiquinone is the less expensive and more stable form of CoQ10.  It is also the form of CoQ10 that has the majority of studies including the studies sited above. 


Science stuff: Ubiquinone is a cofactor in the inner membrane of the mitochondria for the synthesis of energy (ATP). Since the body does not store energy (ATP), it must be rapidly produced through an oxidative phosphorlation process. CoQ10 is positioned between NADH and Cyto-Chrome C in the inner membrane and acts as cofactor stimulation to all three mediators to give up electrons to run the electron transport through complexes I-IV in this system. This function is specific to Ubiquinone in that no other molecule can replace Ubiquinone in this process.3


Great, but which type do you take?


This has been a discussion for years.  Ubiquinol suppliers have been touting that ubiquinol is superior to ubiquinone because it’s more bio-available and ensures optimal absorption.  Studies show otherwise or are at least conflicting.  The fact is, both are equally distributed in the body and more importantly, both are interchangeable by the body.  Our body simply converts ubiquinol to ubiquinone and vice versa when needed.  Ubiquinol is also difficult to keep in its reduced form, which is why it’s so expensive.  Here are Supplement Spot, we have concluded that it makes no difference as long as you are supplementing with a CoQ10, so why not save money and supplement with ubiquinone.


Shameless Plug:  Supplement Spot provides CoQ10 (Ubiquinone) in 100mg, 200mg, 100mg with bioperine(for better absorption), face cream and even an eye cream.  Use coupon code CoQ10 for 10% off your purchase.  Happy shopping!


Live Long and Love Life
Your friends at Supplement Spot

References:

1) www.ncbi.nlm.nih.gov/pubmed/25282031
2) www.ncbi.nlm.nih.gov/pmc/articles/PMC4666408/
3) www.zmc-usa.com/docs/CoQ10_Facts_or_Fabrications.pdf

 

 

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